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How To Prevent And Treat Diabetes

Type 2 diabetes is a chronic disease with many complications, including heart disease and amputations of the digits. Learn the signs and symptoms of this life-threatening illness – plus do a quick test to find out if you have diabetes.

In the last two decades, we’ve seen the prevalence of diabetes dramatically increase. This is due largely to a combination of several public health threats, including obesity, sedentary lifestyle, and sedentariness. But why? What is the biggest factor?

This short article will take you through the typical causes of diabetes, along with strategies that may help reverse the progression of this disease. You’ll learn how this chronic autoimmune disease, the consequence of eating too much sugar, can be avoided and potentially made controllable.

We’ll also talk about some common symptoms of this disease that can be caused by the inflammatory response, inflammation or an autoimmunity.

Type 2 diabetes is a chronic disease of insulin metabolism, which is characterized by a failure to produce sufficient insulin and/or excessive insulin. It is often caused by an autoimmune response to the insulin-producing pancreatic islets of Langerhans. This occurs because of the way humans metabolize sugar in the diet.

The autoimmune pathway occurs for two reasons. First, the cells producing insulin are overwhelmed with excessive glucose from sugar. Secondly, they are “taken over” by tumor necrosis factor alpha, a cytokine that is often secreted into the blood by the immune system. 

When the islets secrete TNFalpha, the islet cells secrete insulin. But the pancreas does not make insulin as well, so the glucose from the diet is not fully used. In an attempt to control high blood sugar and avoid tissue damage to the pancreas and body, insulin secretion increases and glucose levels rise even higher. The pancreas is then unable to produce enough insulin to compensate.

When this happens, the body begins to shut down the islet cells and secrete other factors that are toxic to the insulin producing cells. This leads to an eventual condition called β-cell failure. Type 2 diabetes can occur as soon as 1 year of age, although it can take 2 years or more for the disease to fully develop. 

There are a number of factors that can cause or increase insulin secretion. Some of the biggest factors that can cause chronic high levels of insulin include poor nutrition, high caloric intake, excess physical activity, a sedentary lifestyle, and excessive insulin use (i.e., taking large doses of insulin). 

Sedentary lifestyle: Sitting for a significant time a day or sitting in a stupor from poor diet has long been the norm for most people; even those who exercise little. This type of lifestyle causes insulin levels and blood sugar to rise. But it is not just an increase in insulin and blood sugar; excessive insulin secretion can cause insulin resistance.  Insulin resistance is the main cause of type 2 diabetes. Insulin resistance results when insulin production is reduced as cells become resistant to insulin stimulation. This can result in hypoglycemia; a drop in blood sugar.  This occurs at the levels of fasting blood glucose level in the normal range. People with insulin resistance need to take an antidiabetic drug to ensure that glucose levels stay within the normal range. An antidiabetic drug is an insulin such as a sulfonylurea (Splenda, Sunovid, Lantus, Metrocollagen, etc.) or one of several insulin analogues (which mimic the insulin that is already in the body). The drug is taken each day until the blood glucose levels drop to normal. As the body is already insulin-sensitive, it takes longer to lower blood sugar levels, which also results in more frequent shots.

In the past, insulin was used for this condition, but the side effects were so severe that patients had to be hospitalized. Today, insulin is taken only as a final option if the blood sugar is also too low.